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Exemestane is a medication that belongs to a class of drugs known as aromatase inhibitors. It is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Aromatase inhibitors work by reducing the production of estrogen in the body. Estrogen is a hormone that can promote the growth of certain types of breast cancer cells. Exemestane specifically inhibits the enzyme aromatase, which is responsible for converting androgens (male hormones) into estrogen in postmenopausal women. By blocking this enzyme, Exemestane lowers the levels of estrogen in the body, thereby slowing down the growth of hormone receptor-positive breast cancer cells.
Exemestane is typically taken orally in the form of a tablet, usually once daily. It is often prescribed as part of adjuvant therapy, which is given after surgery or other primary treatments to reduce the risk of cancer recurrence. It may also be used in advanced breast cancer cases where the cancer has spread to other parts of the body.