Letrozole is a medication that belongs to a class of drugs known as aromatase inhibitors. It is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Letrozole works by inhibiting the enzyme aromatase, which is responsible for the conversion of androgens (male hormones) into estrogens (female hormones). By blocking this enzyme, letrozole reduces the production of estrogen in the body. This is important because estrogen can stimulate the growth of hormone receptor-positive breast cancer cells.
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