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IGF-1 DES (Insulin-like Growth Factor-1 Des(1-3)) is a modified form of the naturally occurring hormone IGF-1. It is a peptide hormone that plays a crucial role in growth and development in the human body.
IGF-1 DES is derived from the original IGF-1 molecule by removing the first three amino acids from the N-terminus. This modification makes IGF-1 DES more potent and faster acting compared to the native IGF-1.
IGF-1 DES works by binding to the IGF-1 receptor, which is present on the surface of various cells in the body. This binding activates a signaling cascade that promotes cell growth, proliferation, and differentiation. It also enhances protein synthesis and inhibits cell death (apoptosis).
The shortened structure of IGF-1 DES allows it to have a higher affinity for the IGF-1 receptor, leading to a more potent and localized effect. It has a shorter half-life compared to native IGF-1, which means it remains active for a shorter duration in the body.
IGF-1 DES is primarily used in research settings to study its effects on muscle growth, tissue repair, and metabolism. It is not approved for human use and is considered a banned substance in many sports due to its potential performance-enhancing effects.