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Spironolactone Information

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2D Structure of Spironolactone
2D Structure
3D Structure of Spironolactone
3D Structure

Spironolactone is a medication that belongs to a class of drugs called aldosterone receptor antagonists. It is primarily used as a diuretic (water pill) to treat fluid retention (edema) caused by various conditions such as heart failure, liver disease, and kidney disease.

However, Spironolactone is also commonly prescribed for the treatment of hormonal conditions such as polycystic ovary syndrome (PCOS) and hirsutism (excessive hair growth). It is particularly effective in reducing the production of androgens (male hormones) in the body.

Spironolactone works by blocking the action of aldosterone, a hormone that regulates the balance of salt and water in the body. By inhibiting aldosterone, it causes the kidneys to excrete excess salt and water, reducing fluid retention. Additionally, it acts as an anti-androgen by binding to androgen receptors, preventing the effects of androgens on the body.

In the context of PCOS and hirsutism, Spironolactone helps to reduce the symptoms associated with excess androgens, such as acne, oily skin, and unwanted hair growth. It is important to note that Spironolactone should only be taken under the supervision of a healthcare professional, as it can have potential side effects and interactions with other medications.

Synonyms of Spironolactone

  • spironolactone
  • 52-01-7
  • Aldactone
  • Spirolactone
  • Verospirone
  • Verospiron
  • Euteberol
  • Spirolang
  • Spiroctan
  • Acelat
  • Aldactone A
  • Spironocompren
  • Melarcon
  • Spiresis
  • Spiridon
  • Uractone
  • Urusonin
  • Alderon
  • Spirone
  • Xenalon
  • Dira
  • Spiro-Tablinen
  • Spironolactone A
  • spironolattone
  • Spironolactonum
  • Aquareduct
  • Aldopur
  • Espironolactona
  • Almatol
  • Deverol
  • Aldace
  • Altex
  • Abbolactone
  • Berlactone
  • Veroshpiron
  • Spironolattone [DCIT]
  • Aldactide
  • Diatense
  • Duraspiron
  • Spiractin
  • SC 9420
  • SC-9420
  • Spironolactonum [INN-Latin]
  • Espironolactona [INN-Spanish]
  • Spironolactone ceva
  • C24H32O4S
  • SC9420
  • spirotone
  • Spiroctanie
  • Spirolakton
  • Carospir
  • Diatensec
  • Lacalmin
  • Lacdene
  • Laractone
  • Nefurofan
  • Sagisal
  • Sincomen
  • Spiroderm
  • Spirolone
  • Suracton
  • Supra-puren
  • HSDB 3184
  • EINECS 200-133-6
  • Aldactone (TN)
  • NSC 150399
  • NSC-150399
  • BRN 0057767
  • CHEBI:9241
  • Spironolactone [BAN:INN:JAN]
  • Spironolactone [INN:BAN:JAN]
  • DTXSID6034186
  • UNII-27O7W4T232
  • Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
  • 27O7W4T232
  • quimolactona
  • CHEMBL1393
  • 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
  • SC 15983
  • Spiretic
  • DTXCID4014186
  • 4-18-00-01601 (Beilstein Handbook Reference)
  • Spironolactone [USP:INN:BAN:JAN]
  • NSC150399
  • 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone acetate
  • 3'-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone
  • Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-
  • S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate
  • SNL
  • CARDALIS COMPONENT SPIRONOLACTONE
  • SPIRONOLACTONE COMPONENT CARDALIS
  • ALDACTAZIDE COMPONENT SPIRONOLACTONE
  • 7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
  • SPIRONOLACTONE COMPONENT OF ALDACTAZIDE
  • 3-(3-Keto-7-alpha-acetylthio-17-beta-hydroxy-4-androsten-17-alpha-yl)propionic acid lactone
  • Spiro(17H-cyclopenta(a)phenanthrene-17,2'(5'H)-furan), pregn-4-ene-21-carboxylic acid deriv.
  • SPIRONOLACTONE (IARC)
  • SPIRONOLACTONE [IARC]
  • 17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate
  • 17alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7alpha-mercapto-3-oxo-, gamma-lactone, acetate
  • SPIRONOLACTONE (MART.)
  • SPIRONOLACTONE [MART.]
  • SPIRONOLACTONE (USP-RS)
  • SPIRONOLACTONE [USP-RS]
  • Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
  • Jenaspiron
  • Spirogamma
  • Spirospare
  • Flumach
  • Frumikal
  • Practon
  • Spirobeta
  • Spironone
  • Sprioderm
  • NovoSpiroton
  • Novo Spiroton
  • Novo-Spiroton
  • Spirono Isis
  • Spirono-Isis
  • spiro von ct
  • SPIRONOLACTONE (EP MONOGRAPH)
  • SPIRONOLACTONE [EP MONOGRAPH]
  • SPIRONOLACTONE (USP MONOGRAPH)
  • SPIRONOLACTONE [USP MONOGRAPH]
  • von ct, spiro
  • 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone
  • Verospirone Opianin
  • (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan]-6'-ene-5,5'-dione
  • 17-alpha-Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7-alpha-mercapto-3-oxo-, gamma-lactone acetate
  • SMR000471892
  • Espironolactona Alter
  • SPIRONOLACTONE (EMA EPAR VETERINARY)
  • SPIRONOLACTONE [EMA EPAR VETERINARY]
  • Spiro L.U.T.
  • Espironolactona Mundogen
  • MFCD00082250
  • Prilactone
  • Spiranolactone
  • spironolacton-
  • 2oax
  • 3vhu
  • Berlactone (TN)
  • CAS-52-01-7
  • Verospiron (TN)
  • Spiractin (TN)
  • Spirotone (TN)
  • Aldactazide (TN)
  • NCGC00015948-02
  • 3-(3-Keto-7.alpha.-acetylthio-17.beta.-hydroxy-4-androsten-17.alpha.-yl)propionic acid lactone
  • 7-.alpha.-(acetylthio)-17-.alpha.-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, .gamma.-lactone
  • S-((7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate
  • S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate
  • Novo-Spiroton (TN)
  • Prestwick0_000128
  • Prestwick1_000128
  • Prestwick2_000128
  • Prestwick3_000128
  • D0EP0C
  • SPIRONOLACTONE [MI]
  • Dexo Brand of Spironolactone
  • SPIRONOLACTONE [INN]
  • SPIRONOLACTONE [JAN]
  • BIDD:PXR0071
  • SCHEMBL20939
  • BSPBio_000176
  • SPIRONOLACTONE [HSDB]
  • SPIRONOLACTONE [INCI]
  • Alter Brand of Spironolactone
  • MLS001074672
  • MLS001333253
  • MLS001333254
  • MLS002153245
  • MLS002207058
  • MLS002548846
  • Roche Brand of Spironolactone
  • SPIRONOLACTONE [VANDF]
  • Cardel Brand of Spironolactone
  • Pfizer Brand of Spironolactone
  • Searle Brand of Spironolactone
  • SPBio_002115
  • Worwag Brand of Spironolactone
  • BPBio1_000194
  • GTPL2875
  • SPIRONOLACTONE [WHO-DD]
  • SPIRONOLACTONE [WHO-IP]
  • Alpharma Brand of Spironolactone
  • Hormosan Brand of Spironolactone
  • Mundogen Brand of Spironolactone
  • betapharm Brand of Spironolactone
  • Ashbourne Brand of Spironolactone
  • Azupharma Brand of Spironolactone
  • C03DA01
  • Generosan Brand of Spironolactone
  • Jenapharm Brand of Spironolactone
  • Novopharm Brand of Spironolactone
  • Alphapharm Brand of Spironolactone
  • Pharmafrid Brand of Spironolactone
  • Spironolactone (JP15/USP/INN)
  • Spironolactone (JP17/USP/INN)
  • HMS1568I18
  • HMS2090N21
  • HMS2095I18
  • HMS2236E06
  • HMS3259G11
  • HMS3712I18
  • Merck dura Brand of Spironolactone
  • AMY40521
  • HY-B0561
  • Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, .gamma.-lactone, (7.alpha.,17.alpha.)-
  • Spironolactone, 97.0-103.0%
  • SPIRONOLACTONE [ORANGE BOOK]
  • Tox21_113047
  • Tox21_302154
  • BDBM50228080
  • C24-H32-O4-S
  • HB2799
  • s4054
  • 4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
  • AKOS015896401
  • SPIRONOLACTONUM [WHO-IP LATIN]
  • AC-4214
  • CCG-220128
  • ct Arzneimittel Brand of Spironolactone
  • ct-Arzneimittel Brand of Spironolactone
  • DB00421
  • KS-5234
  • Mayoly-Spindler Brand of Spironolactone
  • NC00482
  • NCGC00164397-01
  • NCGC00164397-02
  • NCGC00164397-03
  • NCGC00164397-05
  • NCGC00255229-01
  • BS166385
  • CPD000471892
  • Spironolactone 1.0 mg/ml in Acetonitrile
  • LS-118614
  • AB00513806
  • LT00772287
  • S0260
  • C07310
  • C75438
  • D00443
  • EN300-123035
  • AB01275520-01
  • AB01275520_02
  • Q422188
  • SR-01000765419
  • SR-05000000452
  • Q-201737
  • SR-01000765419-2
  • SR-05000000452-2
  • BRD-K90027355-001-03-4
  • BRD-K90027355-001-19-0
  • Z1546616196
  • Spironolactone, European Pharmacopoeia (EP) Reference Standard
  • WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
  • 17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone acetate
  • 7alpha-Acetylsulfanyl-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
  • SPIRO(17H-CYCLOPENTA(A)PHENAUTHRENE-17,2'-(3'H)-FURAN
  • Spironolactone, United States Pharmacopeia (USP) Reference Standard
  • 17.alpha.-Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, acetate
  • Pregn-4-ene-21-carboxylic acid, .gamma.-lactone, (7.alpha.,17.alpha.)-
  • (7?,17?)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid ?-lactone
  • Spironolactone for system suitability, European Pharmacopoeia (EP) Reference Standard
  • (1R,3aS,3bR,4R,9aR,9bS,11aS)-4-(acetylsulfanyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydrospiro[cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7-dione
  • (7-alpha,17-alpha)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid gamma-lactone
  • (7<span class='symbol'>alpha</span>,17<span class='symbol'>alpha</span>)-7-(Acetylthio)-17-hydroxy-3- oxopregn-4-ene-21-carboxylic acid <span class='symbol'>gamma</span>-lactone
  • 17-hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid gamma-lactone, acetate
  • 2'',15''-dimethyl-5,5''-dioxo-(9''R)-spiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate
  • 2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate
  • 2'',15''-dimethyl-5,5''-dioxospiro[tetrahydrofuran-2,14''-tetracyclo[8.7.0.02,7.011,15]heptadec-6''-ene]-9-yl ethanethioate(Spiranolactone)
  • PREGN-4-ENE-21-CARBOXYLIC ACID, 7-(ACETYLTHIO)-17-HYDROXY-3-OXO-,.GAMMA.-LACTONE, (7.ALPHA.,17.ALPHA.)-
  • S-(2''R,7R,8R,9S,10R,13S,14S)-10,13-dimethyl-3,5''-dioxo-1,2,3,4'',5'',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3''H-spiro[cyclopenta[a]phenanthrene-17,2''-furan]-7-yl ethanethioate
  • Spiro(17H-cyclopenta(a)phenanthrene-17,2'(5'H)-furan), pregn-4-ene-21-carboxylic acid deriv

External Sources about Spironolactone

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