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Triptorelin Information

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2D Structure of Triptorelin
2D Structure

Triptorelin is a synthetic hormone used in medicine for various purposes. It belongs to a class of drugs called gonadotropin-releasing hormone (GnRH) agonists. GnRH is a hormone produced in the hypothalamus of the brain that stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland.

Triptorelin works by binding to and activating the GnRH receptors in the pituitary gland. Initially, it causes an initial surge in LH and FSH release, which leads to an increase in testosterone or estrogen production. However, with continued use, triptorelin desensitizes the GnRH receptors, leading to a decrease in LH and FSH release. This results in a reduction in testosterone or estrogen levels.

Triptorelin is commonly used in the treatment of hormone-dependent conditions such as prostate cancer, breast cancer, endometriosis, and precocious puberty. It can also be used to suppress ovarian function in assisted reproductive technologies like in vitro fertilization (IVF).

Synonyms of Triptorelin

  • TRIPTORELIN
  • 57773-63-4
  • Triptoreline
  • Arvekap
  • (D-Trp6)-GnRH
  • Decapeptyl
  • Triptorelina
  • Triptorelinum
  • Triptodur
  • Trelstar
  • tryptorelin
  • Diferelin
  • Diphereline
  • CL-118532
  • pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
  • D-Tryptophan-LH-RH
  • AY-25650
  • CL 118532
  • UNII-9081Y98W2V
  • CHEBI:63633
  • Wy 42462
  • Triptoreline [INN-French]
  • Triptorelinum [INN-Latin]
  • Triptorelina [INN-Spanish]
  • AY 25650
  • Pamorelin
  • Salvacyl
  • Trelstar depot
  • Triptorelin [USAN:INN:BAN]
  • 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycinamide
  • CL 118,532
  • BIM 21003
  • Wy 42422
  • 6-D-tryptophan-LH-RH
  • Wy-42462
  • Triptorelin [USAN:BAN:INN]
  • C64H82N18O13
  • C64-H82-N18-O13
  • Trellasar
  • Moapar
  • Decapeptyl SR
  • Pamorelin LA
  • Triptorelin (swine)
  • D-Trp6-LHRH
  • Gonapeptyl depot (TN)
  • Debio-8206
  • Triptorelin (USAN/INN)
  • (D-Trp6)-LH-RH
  • D03QRS
  • GTPL1177
  • SCHEMBL5079698
  • CHEMBL1201334
  • DTXSID2048375
  • SCHEMBL22289009
  • HMS2090C17
  • CS-AD-00553
  • EX-A3857
  • BIM-21003
  • AKOS030213249
  • 9081Y98W2V
  • CS-5745
  • DB06825
  • NCGC00167301-01
  • NCGC00167301-02
  • AS-71149
  • BN-52014
  • HY-12551
  • C75704
  • D06247
  • [D-Trp6]-LH-RH, >=97% (HPLC), powder
  • AB01275488-01
  • A936467
  • EN300-18527985
  • pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-GlyNH2
  • Q1992452
  • (S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6,15-bis((1H-indol-3-yl)methyl)-21-(3-guanidinopropyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-18-isobutyl-1,4,7,10,13,16,19-heptaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20-heptaazadocosan-22-oyl)-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide
  • Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl-

External Sources about Triptorelin

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