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Letrozole Information

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2D Structure of Letrozole
2D Structure
3D Structure of Letrozole
3D Structure

Letrozole is a medication that belongs to a class of drugs known as aromatase inhibitors. It is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women.

Letrozole works by inhibiting the enzyme aromatase, which is responsible for the conversion of androgens (male hormones) into estrogens (female hormones). By blocking this enzyme, letrozole reduces the production of estrogen in the body. This is important because estrogen can stimulate the growth of hormone receptor-positive breast cancer cells.

By lowering estrogen levels, letrozole helps to slow down or stop the growth of breast cancer cells, thereby reducing the risk of cancer recurrence or progression. It is often prescribed as an adjuvant therapy after surgery or as a first-line treatment for advanced or metastatic breast cancer.

Synonyms of Letrozole

  • letrozole
  • 112809-51-5
  • Femara
  • 4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile
  • Letrozol
  • CGS 20267
  • CGS-20267
  • Letoval
  • 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
  • C17H11N5
  • LETRAZOLE
  • Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-
  • Femera
  • 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
  • Letrozole [USAN:INN]
  • 4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
  • Femara (TN)
  • HSDB 7461
  • 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile
  • NSC-759652
  • CHEMBL1444
  • Letrozole (JAN/USP/INN)
  • UNII-7LKK855W8I
  • 4-[(4-CYANOPHENYL)(1H-1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE
  • 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
  • 7LKK855W8I
  • CCRIS 8822
  • CHEBI:6413
  • DTXSID4023202
  • 1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole
  • FEM-345
  • Letrozole [USAN:USP:INN:BAN]
  • LEROZOLE
  • 4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile
  • NCGC00016973-01
  • CAS-112809-51-5
  • 1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole
  • DTXCID503202
  • SMR000466343
  • SR-01000759382
  • Femara, Letrozole
  • Letrozole- Bio-X
  • CGS20267
  • MFCD00866241
  • LETROZOLE [INN]
  • LETROZOLE [JAN]
  • LETROZOLE [MI]
  • LETROZOLE [HSDB]
  • LETROZOLE [USAN]
  • Prestwick0_001025
  • Prestwick1_001025
  • Prestwick2_001025
  • Prestwick3_001025
  • Femara (TN) (Novartis)
  • D0C1WH
  • LETROZOLE [MART.]
  • LETROZOLE [USP-RS]
  • LETROZOLE [WHO-DD]
  • Novartis Brand of Letrozole
  • SCHEMBL4331
  • BIDD:PXR0130
  • BSPBio_001209
  • MLS000759455
  • MLS001424038
  • MLS002584991
  • MLS006010040
  • BIDD:GT0015
  • SPBio_003070
  • BPBio1_001331
  • GTPL5209
  • LETROZOLE [EP IMPURITY]
  • LETROZOLE [ORANGE BOOK]
  • LETROZOLE [EP MONOGRAPH]
  • Letrozole, >=98% (HPLC)
  • BDBM13061
  • EX-A965
  • LETROZOLE [USP MONOGRAPH]
  • 4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
  • HMS1571M11
  • HMS2051E08
  • HMS2089L22
  • HMS2098M11
  • HMS2233C23
  • HMS3369E11
  • HMS3393E08
  • HMS3651K05
  • HMS3715M11
  • Pharmakon1600-01502354
  • AMY32541
  • BCP23354
  • Tox21_110719
  • Tox21_303572
  • 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole
  • NSC719345
  • NSC759652
  • s1235
  • STL451047
  • AKOS005145822
  • AB07525
  • AC-1193
  • BCP9000848
  • C17-H11-N5
  • CCG-100849
  • CS-1776
  • DB01006
  • KS-1269
  • NC00099
  • NSC 759652
  • NSC-719345
  • NCGC00016973-02
  • NCGC00016973-03
  • NCGC00016973-06
  • NCGC00257460-01
  • BL164620
  • HY-14248
  • LS-38788
  • BCP0726000213
  • CGS 20267, Femara, Piroxicam, Letrozole
  • 1-Bis(4-cyanophenyl)methyl-1,2,4-triazole
  • 4,2,4-Triazol-1-ylmethylene)dibenzonitrile
  • AB00514009
  • L0248
  • SW197294-4
  • A25380
  • C08163
  • D00964
  • EN300-264820
  • AB00514009-05
  • AB00514009-07
  • AB00514009-08
  • AB00514009-09
  • AB00514009_10
  • AB00514009_11
  • KISQALI FEMARA CO-PACK COMPONENT LETROZOLE
  • Q194974
  • W-60273
  • 4,4'-(1,2,4-Triazol-1-ylmethylene)dibenzonitrile
  • LETROZOLE COMPONENT OF KISQALI FEMARA CO-PACK
  • Q-201291
  • SR-01000759382-4
  • SR-01000759382-5
  • BRD-K88789588-001-03-2
  • 4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
  • 4,4'-(1h-1,2,4-triazol-1-ylmethylene)-bisbenzonitrile
  • F2173-0288
  • Z1741968261
  • 4,4'-((1H-1,2,4-Triazol-1-yl)-methylene)dibenzonitrile
  • Letrozole, European Pharmacopoeia (EP) Reference Standard
  • Letrozole, United States Pharmacopeia (USP) Reference Standard
  • 4-[1-(4-CYANOPHENYL)-1-(1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE
  • Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material

External Sources about Letrozole

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