Glycyl-L-Histidyl-L-Lysine (GHK) is a naturally occurring human tripeptide, meaning it's a small protein fragment made up of three amino acids: Glycine, L-Histidine, and L-Lysine, joined in that specific sequence (Gly-His-Lys).
It is found in human plasma, saliva, and urine, but its concentration in the plasma declines significantly with age. GHK is particularly well-known for its strong affinity for copper ions, with which it readily forms a complex known as GHK-Cu or Copper Peptide. This copper-peptide complex is the active form used in most research and commercial products, especially in skincare and wound healing.
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